mean reduction from baseline
CLINICALLY STUDIED BOTANICAL METABOLIC SUPPORT
Turn Up Metabolism.
Transform Body Composition.
Theolim® is a proprietary combination of standardized Key Lime rind and Cocoa seed extracts developed by Laila Nutra to support energy expenditure, fat oxidation and healthy body composition.
Clinically studied dose: 450 mg/day. Ingredient information for business and professional audiences.
KEY LIME+COCOA2:1 botanical blend
2Human clinical studies
180Participants across studies
16Week RCT
450 mgClinically studied daily dose
THEOLIM® SCIENCE
Metabolic support that goes beyond the scale.
Theolim® was developed around a multi-pathway approach to metabolism. Human research has evaluated body weight, DEXA-measured body composition, resting metabolic rate, fat oxidation and metabolic biomarkers.
16-WEEK HUMAN RCT
Results you can measure.
Randomized, double-blind, placebo-controlled, multicenter study in 120 overweight adults receiving 450 mg/day.
mean reduction from baseline
mean reduction from baseline
no compromise in mean lean body mass
For comparison, placebo mean changes were −0.96 kg body weight and −0.85 kg total body fat. Study outcomes and statistical context should be considered in full.
Read the peer-reviewed clinical study ↗METABOLIC SIGNALS
More than calories.
A network of signals.
from baseline at week 16
A gut-derived hormone involved in metabolic and satiety signaling.from baseline at week 16
An adipose-derived signaling protein associated with metabolic health.significantly reduced
A hormone involved in hunger and energy-homeostasis signaling.Biomarker changes do not establish drug-like GLP-1 receptor agonism. Theolim® is not a pharmaceutical GLP-1 receptor agonist.
HOW THEOLIM® WORKS
From botanical actives to metabolic response.
Key Lime + CocoaStandardized botanical extracts
→
Metabolic signalingGLP-1 • Adiponectin • Ghrelin
AMPK • FGF-21 • β3-AR*
→
AMPK • FGF-21 • β3-AR*
Metabolic responseEnergy expenditure
Fat oxidation
→
Fat oxidation
Body compositionBody fat • Weight • Waist
Lean mass maintained
Lean mass maintained
*Mechanistic pathways include evidence from preclinical/mechanistic research and should not be interpreted as equivalent to demonstrated human clinical endpoints.
ACUTE HUMAN STUDY
Metabolic activity measured within hours.
A randomized, double-blind, placebo-controlled crossover study in 60 overweight adults evaluated a single 450 mg dose using indirect calorimetry.
View study ↗0Single dose
120RMR difference*
180RMR difference*
ExerciseFat oxidation evaluated
*Statistically significant between-group RMR differences were reported at 120 and 180 minutes.BUILD WITH THEOLIM®
One ingredient. Multiple product opportunities.
Healthy Weight Management
For products focused on healthy weight, body composition, fat metabolism and waist management.
Active Nutrition
For metabolic-performance concepts built around energy expenditure, fat oxidation and body composition.
Metabolic Health
For modern metabolic-wellness platforms looking beyond conventional stimulant-led thermogenics.
Healthy Aging
For body-composition and metabolic-resilience concepts designed for healthy aging portfolios.
FORMULATION
Designed for brand builders.
STUDIED DOSE450 mg/day
BOTANICAL RATIO2:1Key Lime rind : Cocoa seed extracts
FORMATSCapsules • Tablets • BlendsAdditional formats subject to formulation and sensory validation.
SAFETY
Evidence built from development to human use.
The development program includes formal toxicology and human clinical safety monitoring. No major adverse events were reported in the 16-week RCT.
90-DayRepeat-dose toxicology program
GenotoxicityTesting program
HumanClinical safety monitoring
SCIENTIFIC RESOURCES
Follow the evidence.
PARTNER WITH LAILA NUTRA
What will you build with Theolim®?
Talk to our ingredient team about samples, technical documentation, formulation support, commercial supply and market-specific positioning.